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sb-269970 hydrochloride (c15-1768-660)

SB-269970 HYDROCHLORIDE POWDER >=98% (HPLC) (C005B-354058)

Catalog No.
C005B-354058
Mfr. No.
S7389-5MG
Mfr. Name
Sigma-Aldrich
Qty/UOM
5
UOM
MG
Price: $679.21
List Price: $754.68

Application SB-269970 hydrochloride has been used to study the effect of different endotype combination on the activity of the 5-hydroxytryptamine receptor of tall fescue alkaloids. It has also been used to inhibit dopamine receptor signaling, in

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Application

SB-269970 hydrochloride has been used to study the effect of different endotype combination on the activity of the 5-hydroxytryptamine receptor of tall fescue alkaloids. It has also been used to inhibit dopamine receptor signaling, in order to study its role in early hemocyte activation.

SB-269970 was used to study the role of 5-HT7 receptors in serotonin-induced hypothermia in rodents.6

Biochem/physiol Actions

SB-269970 is an anti-psychotic agent that shows high affinity for 5-HT7 receptors. It may be effective in treating cognitive disabilities and schizophrenia-like deficits.4 SB-269970 desensitizes and decreases the excitatory effects of 5-HT7 receptors in rat hippocampus.5

Selective 5-HT7 serotonin receptor antagonist.

Legal Information

Sold with the permission of GlaxoSmithKline Pharmaceuticals

UPC:
51182107
Condition:
New
Availability:
3-5 Days
Weight:
1.00 Ounces
HazmatClass:
No
MPN:
S7389-5MG
CAS:
261901-57-9

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