SB265610 (C005B-313397)

Catalog No.: C005B-313397
Mfr. No.: SML0421-5MG
Mfr. Name: Sigma-Aldrich
Qty/UOM: 5
UOM: MG

Price: $326.12

List Price: $362.35

Application SB265610 has been used: as a cysteine-amino acid-cysteine (CXC)-chemokine receptor type 2 (CXCR2) antagonist to study its effects on the binding of chemokine with G-protein coupled receptors (GPCR) as a CX-chemokine receptor type 1

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Description
Specifications

Application

SB265610 has been used:

as a cysteine-amino acid-cysteine (CXC)-chemokine receptor type 2 (CXCR2) antagonist to study its effects on the binding of chemokine with G-protein coupled receptors (GPCR)
as a CX-chemokine receptor type 1 (CXCR1) inhibitor to study its effect on the chemotactic activity of chemokines on inflammatory cells
as a CXCR2 antagonist to study its effect on migration of neutrophils to the rat brain

Biochem/physiol Actions

SB265610 is a potent and selective CXCR2 chemokine receptor antagonist. It has a Kd = 2.5 nM.

Features and Benefits

This compound is featured on the Chemokine Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

UPC:: 12352202
Condition:: New
Availability:: 3-5 Days
Weight:: 1.00 Ounces
HazmatClass:: No
MPN:: SML0421-5MG
CAS:: 211096-49-0

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