General description
Scandium(III) triflate is an extremely active, efficient, recoverable and reusable acylation catalyst. Its an important catalyst for the Friedel-Crafts acylation, Diels-Alder reactions and other carbon-carbon bond-forming reactions. It also stereochemically catalyzes the radical polymerization of acrylates. Scandium(III) triflate complex of (4′S,5′S)-2,6-bis[4′-(triisopropylsilyl)oxymethyl-5′-phenyl-1′,3′-oxazolin-2′-yl]pyridine has been employed as catalyst for the asymmetric Friedel-Crafts reaction between substituted indoles and methyl (E)-2-oxo-4-aryl-3-butenoates.
Application
Scandium(III) triflate was used as a catalyst in:
- Hydrothiolation reaction of aromatic and aliphatic thiols.
- Selective two-electron reduction of O2 by ferrocene derivatives.
- Vinylogous Friedel-Crafts alkylation of indoles and pyrroles in water.
- Synthesis of β-cyanoketones.
- Combination with triethylsilane to reductively open functionalized pyranoside rings.
- The key steps of synthesis of bullvalone via a stabilized sulfur ylide.
- UPC:
- 51442206
- Condition:
- New
- Weight:
- 1.00 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- 418218-250MG
