General description
As both a nuclear receptor and nuclear transcription factor, Steroidogenic factor-1 (SF-1) serves as an important modulator of steroidogenesis. It has been demonstrated that SF-1 serves as a “master regulator†in varying facets of development and function in both reproductive and adrenal tissues. Immunohistochemical detection of SF-1 in testicular tissue may provide value for distinguishing sex-cord stromal tumors, including Leydig cell, Sertoli cell and granulosa cell neoplasms, from other tumors. In addition, SF-1 detection may have utility in distinguishing primary adrenal cortical lesions from their histologic mimics such as renal clear cell carcinoma.
Quality
![]() IVD | ![]() IVD | ![]() IVD | ![]() RUO |
Physical form
Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide.
Preparation Note
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Other Notes
For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com
Legal Information
Cell Marque is a trademark of Sigma-Aldrich Co. LLC
biological source: rabbit. Quality Level: 100, 500. conjugate: unconjugated. antibody form: culture supernatant. antibody product type: primary antibodies. clone: EP434, monoclonal. description: For In Vitro Diagnostic Use in Select Regions. form: buffered aqueous solution. species reactivity: human. packaging: vial of 0.1 . mL concentrate (462R-14), vial of 0.1 . mL concentrate Research Use Only (462R-14-RUO), vial of 0.5 . mL concentrate (462R-15), vial of 1.0 . mL concentrate (462R-16), vial of 1.0 . mL concentrate Research Use Only (462R-16-RUO), vial of 1.0 . mL pre-dilute Research Use Only (462R-17-RUO), vial of 1.0 . mL pre-dilute ready-to-use (462R-17), vial of 7.0 . mL pre-dilute ready-to-use (462R-18), vial of 7.0 . mL pre-dilute ready-to-use Research Use Only (462R-18-RUO). manufacturer/tradename: Cell Marque™. . technique(s): immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:25-1:100 (concentrated). isotype: IgG. control: adrenocortical carcionma, granulosa cell tumor, testis. shipped in: wet ice. storage temp.: 2-8°C. visualization: nuclear. Gene Information: human ... SF1(7536). Storage Class Code: 12 - Non Combustible Liquids. WGK: WGK 2. Flash Point(F): Not applicable. Flash Point(C): Not applicable.- UPC:
- 41115714
- Condition:
- New
- Weight:
- 1.00 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- 462R-14