SIB-1757

Catalog No.: C005B-344774
Mfr. No.: S9186-10MG
Mfr. Name: Sigma-Aldrich
Qty/UOM: 10
UOM: MG

Price: $314.47

List Price: $349.41

Application SIB 1757 may be used in mGluR5 metabotropic glutamate receptor-mediated cell signaling studies. Biochem/physiol Actions SIB 1757 is a highly selective mGluR5 metabotropic glutamate receptor antagonist.

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Description
Specifications

Application

SIB 1757 may be used in mGluR5 metabotropic glutamate receptor-mediated cell signaling studies.

Biochem/physiol Actions

SIB 1757 is a highly selective mGluR5 metabotropic glutamate receptor antagonist. It non-competitively inhibits glutamate-induced increase in Ca²⁺ at human metabotropic glutamate receptor 1 (hmGluR1).¹ Inhibition of mGlu5 receptor renders protection to neurons² against methamphetamine-induced oxidative damage.³

Features and Benefits

This compound is featured on the Glutamate Receptors (G Protein Family) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

UPC:: 51144128
Condition:: New
Availability:: 3-5 Days
Weight:: 1.00 Ounces
HazmatClass:: No
MPN:: S9186-10MG

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