Sigma-Aldrich

Arginase-1, the protein encoded by the ARG1 gene, is the enzyme that catalyzes the breakdown of L-arginine into ornithine and urea. ARG1 is a key player in the Urea cycle.

Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN (UniProt: P60484 also known as Mutated in multiple advanced cancers 1, Phosphatase and tensin homolog, PTEN) is encoded by the PTEN (also known as

Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN (UniProt: P60484 also known as Mutated in multiple advanced cancers 1, Phosphatase and tensin homolog, PTEN) is encoded by the PTEN (also known as

CDC7, also known as CDC7-related kinase or HsCdc7/HuCdc7, and encoded by the gene CDC7/CDC7L1, is a critical kinase needed to phosphorylate critical substrates that regulate the G1/S phase transition and DNA replication. CDC7 is a serine-threonine

Formin-homology-2-domain containing protein 1 (FHOD1) is a member of the forming homology (FH) family, a group of proteins that act to regulate several cellular processes such as embryonic patterning, cell survival, cytoskeletal organization, gene

S1P lyase is an important enzyme in lipid, steroid, and ceramide metabolism. S1P lyase 1 specifically cleaves phosphorylated sphingoid bases such as sphingosine-1-phosphate into fatty aldehydes and phosphoethanolamine.

Sphingosine kinase 2 (Sphk2), along with its sister enzyme Sphk1, is an important kinase needed to form the important intra and extracellular signaling lipid mediator and neuroprotective factor SPP/S1P (sphingosine 1-phosphate). Sphk2 is important

Lpin2, also known as Phosphatidate phosphatase LPIN2, and encoded by the gene Lpin2, plays important roles in controlling the metabolism of fatty acids. Lpin2 acts as a magnesium-dependent phosphatidate phosphatase enzyme which catalyzes the

Lipin-1 is also called Phosphatidate phosphatase LPIN1. Lipin-1 controls the metabolism of fatty acids, acts as a magnesium-dependent phosphatidate phosphatase enzyme, as well as a nuclear transcriptional coactivator that modulates lipid metabolism

RSK1, RSK2, RSK3, and RSK4 (ribosomal protein S6 kinase, 90 kDa, polypeptide 1,2,3, and 4 S6K-alpha 1,2,3, and 4) are Ser/Thr kinases which are activated by MAP Kinases. Ribosomal S6-kinase 4 (RSK4) is thought to be mapped in the critical region

SLC5A3, also known as Sodium/myo-inositol cotransporter, Na (+)/myo-inositol cotransporter, Sodium/myo-inositol transporter 1 (SMT1), or Solute carrier family 5 member 3, and encoded by the gene SLC5A3, is an important intracellular transporter and

Asymmetric dimethylation of arginine side chains in proteins is a frequent posttranslational modification, catalyzed by type I protein arginine methyltransferases (PRMTs). PRMT8 is a membrane-associated arginine methyltransferase that can both