Sigma-Aldrich

Exchange protein directly activated by cAMP 1 (EPAC1) is also known as Rap guanine nuclear exchange factor 3 and cAMPGEF-I. EPAC1 is a guanine nucleotide exchange factor (GEF) for RAP1A and RAP2A small GTPases which are activated through cAMP

Disrupted in schizophrenia 1 protein (DISC1) is involved in the regulation of multiple aspects of embryonic and adult neurogenesis. DISC1 may play a role as a modulator of the AKT-mTOR signaling pathway controlling the tempo of the process of

N-acylsphingosine amidohydrolase (Acid ceramidase) 1, or ASAH1 is part of a family of hydrolyases, localized in the lysosome, that catalyze the degradation of ceramide into sphingosine (SPH) and free fatty acid. Ceraminde is a subgroup of

C-X3-C motif chemokine 1 (CX3CL1), also known as CX3C membrane-anchored chemokine, Neurotactin (NTT), Small-inducible cytokine D1 (SCYD1), and Fractalkine (FKN), is a CX3C chemokine known to induce adhesion and migration of leukocytes. Recent

Nanos homolog 2 (NANOS2) is a zinc-finger containing, RNA-binding protein belonging to the nanos family. NANOS2 plays an important role in the sexual differentiation of germ cells by promoting the male fate but suppressing the female fate.

Phosphatidylinositol-binding clathrin assembly protein (PICALM), also known as the clathrin assembly lymphoid myeloid leukemia (CALM) protein, co-localizes with clathrin at clathrin-coated areas of the plasma membrane and in the Golgi area as a

Inositol-requiring protein 1 (IRE1p), also known as Ire1-alpha (IRE1a), Endoplasmic reticulum-to-nucleus signaling 1 (ERN1), and Serine/threonine-protein kinase/endoribonuclease IRE1, contains 1 KEN domain and 1 protein kinase domain. IRE1p has an

The Dopamine D2 Receptor is one of the five types (D1 to D5) of receptors for dopamine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase.

The protein named Choline Transporter or Hemicholinium-3-sensitive choline transporter (CHT), and encoded by the gene SLC5A7/CHT1, is the high affinity choline transporter in neurons. Choline is the rate limiting step in acetylcholine synthesis an

Peptide YY (UniProt P10082 also known as Peptide tyrosine tyrosine, PYY, PYY-I) is encoded by the PYY (also known as PYY1) gene (Gene ID 5697) in human. Peptide YY is initially produced as a preproprotein with a signal and a propeptide sequence

Microtubule-associated protein tau (UniProt P10636 also known as Neurofibrillary tangle protein, Paired helical filament-tau, PHF-tau) is encoded by the MAPT (also known as TAU, MAPT1, MTBTL) gene (Gene ID 4137) in human. In Alzheimer&#8242s

Microtubule-associated protein tau (UniProt P10636 also known as Neurofibrillary tangle protein, Paired helical filament-tau, PHF-tau) is encoded by the MAPT (also known as TAU, MAPT1, MTBTL) gene (Gene ID 4137) in human. In Alzheimer&#8242s