Rat anti Mouse SIRP alpha/CD172a Antibody, Monoclonal (P84), could be used for in vivo SIRPα blocking, in vitro SIRPα blocking, WB, IP, Flow and so on.Application:in vivo SIRPα blocking: Use at an assay dependent concentration. in vitro SIRPα blocking: Use at an assay dependent concentration. WB: Use at an assay dependent concentration. IP: Use at an assay dependent concentration. Flow: Use at an assay dependent concentration. Protein FunctionImmunoglobulin-like cell surface receptor for CD47. Acts as docking protein and induces translocation of PTPN6, PTPN11 and other binding partners from the cytosol to the plasma membrane. Supports adhesion of cerebellar neurons, neurite outgrowth and glial cell attachment. May play a key role in intracellular signaling during synaptogenesis and in synaptic function (By similarity). Involved in the negative regulation of receptor tyrosine kinase-coupled cellular responses induced by cell adhesion, growth factors or insulin. Mediates negative regulation of phagocytosis, mast cell activation and dendritic cell activation. CD47 binding prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells.
Specification: ExactAb™, Validated, Carrier Free, Azide Free, ≥95%(SDS-PAGE), Lot by Lot
Related Documents: https://ald-pub-files.oss-cn-shanghai.aliyuncs.com/aladdinsci/pdp/sds/1/AB127636-SCI_e2cc8f2e359da7d2169d4c31af7a1e10.pdf
- UPC:
- 51263111
- Condition:
- New
- Availability:
- 4-8 weeks
- Weight:
- 0.07 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- Ab127636-1mg
- Product Size:
- 1mg
