Application
TFCS-Na is a diversification reagent for the C-H Functionalization of several classes of heterocycles. This reagent installs the trifluoromethylcyclopropyl group, which was recently reported to increase metabolic stability compared to compounds containing the tert-butyl group.
Simple Sulfinate Synthesis Enables C-H Trifluoromethylcyclopropanation
reaction type: C-H Activation. mp: 287-292 . °C. SMILES string: [O-]S(C1(CC1)C(F)(F)F): O.[Na+]. InChI: 1S/C4H5F3O2S.Na/c5-4(6,7)3(1-2-3)10(8)9. /h1-2H2,(H,8,9). /q. +1/p-1. InChI key: IZLDENBRBYPDNY-UHFFFAOYSA-M. Pictograms: GHS07. Signal Word: Warning. Hazard Statements: H315 - H319 - H335. Precautionary Statements: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338. Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3. Target Organs: Respiratory system. Storage Class Code: 11 - Combustible Solids. WGK: WGK 3. Flash Point(F): Not applicable. Flash Point(C): Not applicable.
- UPC:
- 51362407
- Condition:
- New
- Weight:
- 1.00 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- 790184-500MG