Application
Sodium chlorite (NaClO2) can be used as an oxidizing agent for the conversion of:
- Aldehydes to corresponding carboxylic acids under mild reaction conditions in the presence of scavengers such as sulfamic acid or resorcinol.
- Primary alcohols to carboxylic acids in the presence of 2,2,6,6-tetramethylpiperidine-1-oxyl (TEMPO) and NaOCl.
- Aliphatic and aromatic thiols to the corresponding disulfides.
- Aryl boronic acids to phenols via ipso-hydroxylation.
- Cyclic benzylic ethers and N-protected cyclic benzylic amines to benzolactones and benzolactams.
- Alkenes to epoxides using aldehydes as promoters.
- Alkenes and cycloalkenes to 1, 2 diols via osmium-catalyzed Sharpless asymmetric dihydroxylation.
It can also be used in combination with Br2 to synthesize 2-carboxyazetidin-2-ones from furanylazetidinones.
Analysis Note
Assay (iodometric): 23.0 - 26.0 %
Density (d 20 °C/ 4 °C): 1.200 - 1.220
- UPC:
- 51191574
- Condition:
- New
- Weight:
- 1.00 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- 8148151000