General description

Sodium phosphate dibasic is a sodium salt of phosphoric acid. It is highly hygroscopic and water-soluble compound used as a texturizer, emulsifier, and buffer. It can also be used as a reagent in water softeners, cleaners, and boiler treatments process.

Sodium phosphate is widely used buffer in molecular biology, biochemistry, and chromatographic studies. It exists in three forms: monobasic (NaH₂PO₄), dibasic (Na₂HPO₄), and tribasic (Na₃PO₄). Monobasic and dibasic forms in varying ratios are commonly used to compose the neutral sodium phosphate buffer solution.

Application

Sodium phosphate dibasic can be used:

As an efficient and low-cost catalyst for the synthesis of 2-aminochrome by the reaction between aromatic aldehyde, malononitrile, and α- or β-naphthol under solvent-free conditions.
As a buffer in the synthesis of cyclic, acyclic enones and α, β-unsaturated aldehydes from trimethylsilyl enol ethers by using palladium as a catalyst and oxone as oxidant.
As an efficient catalyst in the synthesis of 3,4-dihydropyrano[3,2-c] chromenes from aldehydes, malononitrile and 4-hydroxycoumarin.
As a phosphorous precursor with the phosphoric acid in the synthesis of hydroxyapatite by precipitation method using anionic surfactant SDS (sodium dodefcyl sulfate).