General description
Sophoricoside is an isoflavone glycoside found in the fruit of Sophora japonica. It is a structural isomer of genistin.
Biochem/physiol Actions
Sophoricoside (SOP) improves lipopolysaccharides (LPS)-induced acute lung injury (ALI) in mice by activating the adenosine monophosphate-activated protein kinase (AMPK)/nuclear factor erythroid 2-related factor 2 (Nrf2) signaling pathway. It also improves contact dermatitis by inhibiting the nuclear factor-kappa B (NF-κB) pathway in B cells in mice model.
Sophoricoside elicits anti-cancer, immunosuppressive, and anti-inflammatory activities. It inhibits proinflammatory cytokine production in human mast cells and has the potential to treat allergic inflammation diseases.
- UPC:
- 51112008
- Condition:
- New
- Availability:
- 3-5 Days
- Weight:
- 1.00 Ounces
- HazmatClass:
- No
- MPN:
- SMB00438-25MG
- CAS:
- 152-95-4
