Soyasaponin II

Soyasaponin II is a saponin with antiviral activity. Soyasaponin II inhibits the replication of HSV-1 , HCMV, influenza virus , and HIV-1 . Soyasaponin II shows potent inhibition on HSV-1 replication. Soyasaponin II serves as a inhibitor for YB-1 phosphorylation and NLRP3 inflammasome priming and could protect mice against LPS/GalN induced acute liver failureIn VitroSoyasaponin II inhibits the replication of HSV-1 (IC 50 =54μM), HCMV (104μM), influenza virus (88μM), and HIV-1 (112 μM). MCE has not independently confirmed the accuracy of these methods. They are for reference only.In VivoSoyasaponin II (5 mg/kg; p.o.; once a day for three consecutive days) ameliorates canonical NLRP3 inflammasome-associated innate immune response. MCE has not independently confirmed the accuracy of these methods. They are for reference only.Form:SolidIC50& Target:HSV-1|54 μM (IC|50|)|HIV-1|112 μM (IC|50|)|influenza virus|88 μM (IC|50|)|HCMV|104 μM (IC|50|)|NLRP3 inflammasome. Specification: 0.99 Molecular Formula: C47H76O17 Molecular Weight: 913.1 PubChem CID: 443614 Isomeric SMILES: C[C@H]1[C@@H]([C@H]([C@H]([C@@H](O1)O[C@@H]2[C@H]([C@H](CO[C@H]2O[C@@H]3[C@H]([C@@H]([C@H](O[C@H]3O[C@H]4CC[C@]5([C@H]([C@@]4(C)CO)CC[C@@]6([C@@H]5CC=C7[C@]6(CC[C@@]8([C@H]7CC(C[C@H]8O)(C)C)C)C)C)C)C(=O)O)O)O)O)O)O)O)O