A potent, selective inhibitor of SPHK 1 with anti-proliferative activity; exhibits non-ATP-competitive inhibition of human recombinant GST-SPHK 1 with an IC50 value of 0.5 µM, with no inhibition against ERK2, PI3K or PKCα at concentrations up to 60 µM; inhibits proliferation of human cancer cell lines (T-24, MCF-7, NCI/ADR, and MCF-7/VP) with IC50 values in the low µM range (0.9-4.6 µM).
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- UPC:
- 51172115
- Condition:
- New
- Availability:
- 3 Days
- Weight:
- 1.00 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- 10009222-5
- CAS:
- 312636-16-1
- Model Number:
- C835H61
- Temperature Control Device:
- Yes
