SRI-41315 (C005B-309202)

Catalog No.: C005B-309202
Mfr. No.: SML3312-5MG
Mfr. Name: Sigma-Aldrich
Qty/UOM: 5
UOM: MG

Price: $298.04

List Price: $331.16

Biochem/physiol Actions SRI-41315 is a cell penetrant and potent readthrough agents that suppress translation termination at premature termination codon and allows translation elongation to continue in the correct reading frame and generate a

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Description
Specifications

Biochem/physiol Actions

SRI-41315 is a cell penetrant and potent readthrough agents that suppress translation termination at premature termination codon and allows translation elongation to continue in the correct reading frame and generate a full-length protein. SRI-41315 induces the translational pause that occurs at premature termination codons by depleting eRF1 protein levels through a proteasome-mediated degradation pathway. SRI-41315 restores CFTR expression and function in in immortalized and primary human bronchial epithelial cells.

UPC:: 12352200
Condition:: New
Availability:: 3-5 Days
Weight:: 1.00 Ounces
HazmatClass:: No
MPN:: SML3312-5MG
CAS:: 1613509-49-1

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