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srs11-92 (c09-1044-555)

SRS11-92 (C09-1044-555)

Aladdin

Catalog No.
C09-1044-555
Manufacturer No.
S414492-50mg
Manufacturer Name
Aladdin Scientific
Quantity
1
Unit of Measure
EA
Price: $717.48
List Price: $797.20

InformationSRS11-92 SRS11-92 (AA9), a Ferrostatin-1 (Fer-1) analogue, is a potent inhibitor of ferroptosis . SRS11-92 inhibits ferroptotic cell death induced by Erastin in HT-1080 human fibrosarcoma cells with EC50 of 6 nM.TargetsHT-1080 ferroptotic

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InformationSRS11-92 SRS11-92 (AA9), a Ferrostatin-1 (Fer-1) analogue, is a potent inhibitor of ferroptosis . SRS11-92 inhibits ferroptotic cell death induced by Erastin in HT-1080 human fibrosarcoma cells with EC50 of 6 nM.TargetsHT-1080 ferroptotic cell death (Cell-based assay) 6 nM(EC50)In vitroSRS11-92 is efficacious in protecting human and mouse cellular models of FRDA treated with ferric ammonium citrate (FAC) and an inhibitor of glutathione synthesis (BSO). SRS11-92 decreases the cell death associated with frataxin knockdown in healthy human fibroblasts.Cell Research(from reference)Cell lines：murine I154F FRDA fibroblasts Concentrations：50 μM to 500 nM Incubation Time：48 h. Specification: 0.98 Molecular Formula: C22H28N2O2 Molecular Weight: 352.47 PubChem CID: 71745064 Isomeric SMILES: CCOC(=O)C1=CC(=C(C=C1)NC2CCCCC2)NCC3=CC=CC=C3
UPC:
12352005
Condition:
New
Availability:
1 day
Weight:
0.96 Ounces
HazmatClass:
No
WeightUOM:
LB
MPN:
S414492-50mg
CAS:
1467047-25-1
Product Size:
50mg

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