General description
Suitable for use as a potent inhibitor of PKC and other protein kinases in vitro and in cultured cells.
Application
Staurosporine has been used as a protein kinase inhibitor to study the ubiquitin-protein ligase E3 component N-recognin 5 (UBR5)-mediated CDC73 regulation at the protein level.
Biochem/physiol Actions
Staurosporine, a broad-spectrum protein kinase inhibitor, belongs to the indolocarbazole family. It is referred to as a prototypical ATP-competitive kinase inhibitor. Staurosporine is effective against various kinds of cancers. It is commonly used for inducing apoptosis in different types of cells.
Quality
Routinely evaluated by Protein Kinase Inhibition Assay
Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
- UPC:
- 51392502
- Condition:
- New
- Weight:
- 1.00 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- 19-123