STEARDA inhibits arachidonate 5-LO (5-lipoxygenase) with an IC|50|of 16 nM. Adiditionally, is an ndogenous fatty acid dopamide that displays 'entourage' effects on endovanilloids NADA and anandamide. STEARDA is inactive at TRPV1 and CB1 receptors (at concentrations up to 5 μM) and does not inhibit AMT or FAAH (IC50 > 25 μM). However, STEARDA potentiates TRPV1-mediated effects of NADA in vitro and in vivo; enhances effects on intracellular Ca2+ (EC50 lowered 3-fold) and nociception. Also, STEARDA inhibits arachidonate 5-lipoxygenase (IC50 = 16 nM).application：STEARDA is a novel, endogenous capsaicin-like lipid that produces hyperalgesia. Specification: ≥92% Molecular Formula: C26H45NO3 Molecular Weight: 419.64 PubChem CID: 10025103 Isomeric SMILES: CCCCCCCCCCCCCCCCCC(=O)NCCC1=CC(=C(C=C1)O)O Related Documents: https://ald-pub-files.oss-cn-shanghai.aliyuncs.com/aladdinsci/pdp/sds/1/S334621-SCI_f6908a0e7d78fdab5ff14c063308bd06.pdf
- UPC:
- 12352005
- Condition:
- New
- Availability:
- 2 weeks
- Weight:
- 0.98 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- S334621-500mg
- CAS:
- 105955-10-0
- Product Size:
- 500mg
- Precautionary Statement Codes:
- P264
