Biochem/physiol Actions
Sultopride is an orally active benzamide class dopamine receptor D2/3-selective antagonist (Ki = 18 nM/rat D2, 22 nM/human D3, 7.7 μM/human D4, >10 μM/rat D1 by competitive binding against 0.5 nM Spiperone, 0.2 nM YM-09151-2, 5 nM Spiperone, 0.2 nM SCH23390 for respective receptor) that displays in vivo antipsychotic efficacy with moderate atypical index. Sultopride exhibits little or no affinity toward 5-HT1A2/33, adrenaline receptor α1/α2, Ach receptor, histamine receptor H1, or Sigma receptors σ1/σ2. Sultopride is a racemic material composed of the highly active (-) and the less potent (+) enenatiomers.
- UPC:
- 51331707
- Condition:
- New
- Availability:
- 3-5 Days
- Weight:
- 1.00 Ounces
- HazmatClass:
- No
- MPN:
- SML2741-10MG
- CAS:
- 23694-17-9
