SUN11602 (C005B-308771)

Catalog No.: C005B-308771
Mfr. No.: SML3566-50MG
Mfr. Name: Sigma-Aldrich
Qty/UOM: 1
UOM: EA

Price: $690.44

List Price: $767.15

Biochem/physiol Actions SUN11602 is an orally active basic fibroblast growth factor (bFGF, FGF2) mimetic that protects against glutamate toxicity in primary rat cerebrocortical neuron (0.1-1 μ:M SUN11602: 150 μ:M glutamate) and murine

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Biochem/physiol Actions

SUN11602 is an orally active basic fibroblast growth factor (bFGF, FGF2) mimetic that protects against glutamate toxicity in primary rat cerebrocortical neuron (0.1-1 μM SUN11602; 150 μM glutamate) and murine hippocampal neuron cultures (0.3-3 μM SUN11602; 100 μM glutamate). When administered in vivo, SUN11602 exhibits therapeutic efficacy in a rat hippocampal-lesion model (1-10 mg/kg p.o. 24h post Aβ1-40 injection) and a murine MPTP-induced nigrostriatal degeneration model (2.5-5 mg/kg/day p.o.).

UPC:: 51183702
Condition:: New
Availability:: 3-5 Days
Weight:: 1.00 Ounces
HazmatClass:: No
MPN:: SML3566-50MG
CAS:: 704869-38-5

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