SYUIQ-5 (C005B-362237)

Catalog No.: C005B-362237
Mfr. No.: S5826-5MG
Mfr. Name: Sigma-Aldrich
Qty/UOM: 5
UOM: MG

Price: $576.67

List Price: $640.74

Application SYUIQ-5 may be used in autophagy and DNA damage-inducing cell signaling studies. Biochem/physiol Actions SYUIQ-5 is a Cryptolepine derivative, which induces and stabilizes G-quadruplexes.

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Description
Specifications

Application

SYUIQ-5 may be used in autophagy and DNA damage-inducing cell signaling studies.

Biochem/physiol Actions

SYUIQ-5 is a Cryptolepine derivative, which induces and stabilizes G-quadruplexes. In CNE2 and HeLa cancer cells SYUIQ-5 triggers rapid and potent telomere DNA damage through TRF2 delocalization from telomeres and induces cell death by autophagy. In low concentration the compound caused senescence and telomere shortening. It is a potent cytotoxic agent.

UPC:: 51152111
Condition:: New
Availability:: 3-5 Days
Weight:: 1.00 Ounces
HazmatClass:: No
MPN:: S5826-5MG
CAS:: 188630-47-9

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