T-00127_HEV1 is a phosphatidylinositol 4-kinase III beta ( PI4KB ) inhibitor with an IC 50 of 60 nM.In VitroT-00127_HEV1 shows more potent anti-poliovirus (PV) activity (EC 50 of 0.77 μM) than other candidate compounds (EC 50 of 1.7 to 4.7 μM). GW5074 and T-00127_HEV1 almost completely inhibit PI4KB kinase activity at 10 μM (3% and 5% of residual activity, respectively), in contrast to AN-12-H5 (108% of activity [no inhibition]). MCE has not independently confirmed the accuracy of these methods. They are for reference only.Form:SolidIC50& Target:PI4KB 60 nM (IC 50 ). Specification: 0.99 Molecular Formula: C22H29N5O3 Molecular Weight: 411.5 PubChem CID: 4904109 Isomeric SMILES: CC1=NC2=C(C(=NN2C(=C1)NCCN3CCOCC3)C)C4=CC(=C(C=C4)OC)OC
- UPC:
- 12352005
- Condition:
- New
- Availability:
- 8-12 weeks
- Weight:
- 1.06 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- T647156-50mg
- CAS:
- 900874-91-1
- Product Size:
- 50mg
