T-0080 (C005B-309241)

Catalog No.: C005B-309241
Mfr. No.: SML3283-5MG
Mfr. Name: Sigma-Aldrich
Qty/UOM: 1
UOM: EA

Price: $189.32

List Price: $210.36

Biochem/physiol Actions T-0080 is a blood-brain barrier (BBB)-permeable formyl peptide receptor 1 (FPR1) antagonist that effectively inhibits fMLF-dependent response in human and murine neutrophils cultures (10 nM fMLF-induced human neutrophil

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Description
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Biochem/physiol Actions

T-0080 is a blood-brain barrier (BBB)-permeable formyl peptide receptor 1 (FPR1) antagonist that effectively inhibits fMLF-dependent response in human and murine neutrophils cultures (10 nM fMLF-induced human neutrophil Ca2+ response IC50 = 0.85 μM) and attenuates brain edema and improved neurological outcomes in murine intracerebral hemorrhage (ICH) models in vivo (5 mg/kg via daily i.p.) with no short-term adverse effects (up to 2 g/kg p.o.).

UPC:: 51142426
Condition:: New
Availability:: 3-5 Days
Weight:: 1.00 Ounces
HazmatClass:: No
MPN:: SML3283-5MG

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