General description
tBuBrettPhos is a dialkylbiaryl phosphine ligand developed by the Buchwald group. It promotes cross-coupling reactions more efficiently and exhibits improved reactivity compared to other catalytic systems.
tBuBrettPhos is a phosphine ligand widely used in palladium-catalyzed cross-coupling reactions.
Application
Buchwald Phosphine Ligands for chemical Synthesis
- Buchwald-Hartwig amination and C-O coupling
- Suzuki, Negishi, Stille, Hiyama, Sonogashira cross-couplings
- α-Arylation reaction
New Applications:
- Conversion of aryl and vinyl triflates to bromides and chlorides
- Conversion of aryl triflates to aryl fluorides
- O-Arylation of ethyl acetohydroximate
- Conversion of aryl chlorides and sulfonates to nitroaromatics
Features and Benefits
- White crystalline solid
- Air- and moisture-stable
- Thermally stable
- Highly efficient
- Wide functional group tolerance
- Excellent selectivity and conversion
Legal Information
Usage subject to US Patent 7,858,784
- UPC:
- 41121815
- Condition:
- New
- Weight:
- 1.00 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- 730998-500MG
