Application
Amine functionalized trans-cyclooctene derivative for incorporation of the cyclooctene moiety into carboxyl containing compounds or biomolecules via standard coupling techniques (DCC; EDC etc...). Trans-cyclooctenes are useful in strain-promoted copper-free click chemistry cycloaddition reactions with 1; 2; 4; 5-tetrazines. This cyclooctene will react with tetrazine functionalized compounds or biomolecules without the need for a catalyst to result in a stable covalent linkage. The 4+2 inverse electron demand Diels-Alder cycloaddition between trans-cyclooctene and tetrazines is the fastest biologically compatible ligation technology reported and has had many applications in biological labeling and imaging.
Molecular Weight: 262.78. Empirical Formula: C12H22N2O2 · HCl. form: solid. Quality Level: 100. reaction suitability: reaction type: click chemistry, reagent type: linker. functional group: amine. storage temp.: −. 20°C. SMILES string: O: C(NCCCN)OC1CCC/C: C/CC1.[H]Cl. InChI: 1S/C12H22N2O2.ClH/c13-9-6-10-14-12(15)16-11-7-4-2-1-3-5-8-11. /h1-2,11H,3-10,13H2,(H,14,15). 1H/b2-1+. . InChI key: GIYQQURLGCGUKK-TYYBGVCCSA-N. Pictograms: GHS07. Signal Word: Warning. Hazard Statements: H302. Hazard Classifications: Acute Tox. 4 Oral. Storage Class Code: 11 - Combustible Solids. WGK: WGK 3. Flash Point(F): Not applicable. Flash Point(C): Not applicable.- UPC:
- 51434106
- Condition:
- New
- Weight:
- 1.00 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- 790451-50MG