TCS 21311 (NIBR3049) is a potent, highly selective JAK3 inhibitor with an IC50 of 8 nM, it displays >100-fold selectivity over JAK1, JAK2 and TYK2. TCS 21311 (NIBR3049) inhibits PKCα, PKCθ, and GSK3β with IC50s of 13, 68, and 3 nM, respectively.
Specifictaions: Moligand™, ≥98%
MDL Number: C₂₇H₂₅F₃N₄O₄
Molecular Formula: 526.51
PubChem CID: 50925411
Isomeric SMILES: CC(C)(C(=O)N1CCN(CC1)C2=CC(=C(C=C2)C(F)(F)F)C3=C(C(=O)NC3=O)C4=CNC5=CC=CC=C54)O
Related Documents: https://ald-pub-files.oss-cn-shanghai.aliyuncs.com/aladdinsci/pdp/sds/1/T287291-SCI_d27ea828188536099d5979647ad10708.pdf
- UPC:
- 42201851
- Condition:
- New
- Availability:
- 4-8 weeks
- Weight:
- 1.06 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- T287291-100mg
- CAS:
- 1260181-14-3
- Product Size:
- 100mg