TENIPOSIDE (C005B-313161)

Catalog No.: C005B-313161
Mfr. No.: SML0609-10MG
Mfr. Name: Sigma-Aldrich
Qty/UOM: 10
UOM: MG

Price: $178.83

List Price: $198.70

Application Teniposide has been used as a topoisomerase II inhibitor to study its effects on the flagellum length in Trypanosoma brucei . It has also been used as a chemotherapeutic agent to study its interactions with piperazine(B87).

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Description
Specifications

Application

Teniposide has been used as a topoisomerase II inhibitor to study its effects on the flagellum length in Trypanosoma brucei. It has also been used as a chemotherapeutic agent to study its interactions with piperazine(B87).

Biochem/physiol Actions

Teniposide (VM-26) is a Topoisomerase II inhibitor with antitumor activity. Teniposide inhibits DNA synthesis by forming a complex with topoisomerase II and DNA, inducing breaks in double stranded DNA and preventing repair.

Teniposide is a derivative of podophyllotoxin and has been studied to treat several cancers. It acts during the late S phase or the early G2 phase of the cell cycle.

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UPC:: 12352204
Condition:: New
Availability:: 3-5 Days
Weight:: 1.00 Ounces
HazmatClass:: No
MPN:: SML0609-10MG
CAS:: 29767-20-2
Temperature Control Device:: Yes

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