Thioacetic acid (C09-1051-421)

Thioacetic acid (TAA) can undergo:• Enantioselective addition to nitroalkenes to form chiral 1,2-aminothiol derivatives in the presence of a novel sulfinyl urea organocatalyst. This method has been successfully employed in the synthesis of antifungal drug, sulconazole.• Asymmetric Michael addition reaction with chalcones in the presence of a bifunctional amine thiourea catalyst to form synthetically useful thioesters.• Asymmetric 1,6-conjugate addition with para-quinone methides in the presence of a chiral phosphoric acid catalyst to form chiral sulfur-containing diphenylmethane-type compounds.• Conjugate addition to methacrylamides with chiral trans-2,5-disubstituted pyrrolidine auxiliaries to form chiral β-mercaptocarboxylic acid derivatives.Thioacetic acid is a reagent for introduction of the thiol group into organic molecules.A reagent for introduction of the thiol group into organic molecules. Specification: 0.95 MDL Number: MFCD00004853 Molecular Formula: C2H4OS Molecular Weight: 76.12 EC Number: 208-063-8 PubChem CID: 10484 Isomeric SMILES: CC(=O)S Beilstein Registry Number: 2230 Related Documents: https://ald-pub-files.oss-cn-shanghai.aliyuncs.com/aladdinsci/pdp/sds/1/T112604-SCI_7ab2a751ee7a76a2958da3a1181f9b49.pdf