InformationTianeptine Tianeptine (S-1574, JNJ-39823277, TPI-1062) is an antidepressant agent that act as an atypical agonist of the μ-opioid receptor with clinically negligible effects on the δ- and κ-opioid receptors.Targets5-HT ; μ-opioid receptor (for human μ-opioid receptor) ; 383 nM(Ki)In vitroTianeptine modulates glutamatergic transmission. It restores stress-induced reduction of dendritic arborization in hippocampal neurons and reverses stress-induced inhibition of long-term potentiation at excitatory synapses in the hippocampus and prefrontal cortex. Tianeptine is a serotonin reuptake enhancer and has an antidepressant efficacy.In vivoIn preclinical studies, tianeptine has beneficial effects in a number of behavioral models related to depression, anxiety and other stress-related disorders. Specification: 0.98 Molecular Formula: C21H25ClN2O4S Molecular Weight: 436.95 PubChem CID: 68870 Isomeric SMILES: CN1C2=CC=CC=C2C(C3=C(S1(=O)=O)C=C(C=C3)Cl)NCCCCCCC(=O)O
- UPC:
- 12352005
- Condition:
- New
- Availability:
- 1 day
- Weight:
- 1.09 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- T413226-1g
- CAS:
- 72797-41-2
- Product Size:
- 1g
