Tissue Factor, Apo-, Human, Recombinant, S. frugiperda (C15-1307-047)

General description

M.W. 35,000-37,000.

Recombinant, human apo-tissue factor expressed in S. frugiperda insect cells using a baculovirus expression system. Cell-surface protein of endothelial cells and monocytes involved in coagulation and inflammation. Primary cellular initiator of coagulation protease cascade. Functions as receptor and cofactor for coagulation Factors VII and VIIa. Requires lipidation for clotting assays or other functional activities.

Recombinant, human apo-tissue factor expressed in S. frugiperda insect cells using a baculovirus expression system. Cell-surface protein of endothelial cells and monocytes involved in coagulation and inflammation. Primary cellular initiator of coagulation protease cascade. Requires lipidation for clotting assays or other functional activities. Functions as receptor and cofactor for coagulation Factors VII and VIIa.

Warning

Toxicity: Standard Handling (A)

Physical form

Solid lyophilized from 200 mM mannitol, 150 mM NaCl, 10 mM Tris-HCl, 0.01% CHAPS, pH 8.0.

Reconstitution

Following reconstitution, aliquot and freeze (-20°C).

Reconstitute with 1 ml distilled H₂O

Other Notes

Wildgoose, P., et al. 1993. Biochemistry 32, 114.
Neuenschwander, PF., et al. 1993. J. Biol. Chem.268, 21489.
Yamamoto, M., et al. 1992. J. Biol. Chem.267, 19089.
Morrissey, J., et al. 1991. Thrombosis Res.52, 247.
Drake, T.A., et al. 1989. J. Cell Biol.109, 389.
Bach, R., et al. 1981. J. Biol. Chem.256, 8324.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.

Assay: ≥. 95% (SDS-PAGE). Quality Level: 100. form: lyophilized. manufacturer/tradename: Calbiochem^®. . storage condition: OK to freeze. shipped in: ambient. storage temp.: −. 20°C. Storage Class Code: 13 - Non Combustible Solids. WGK: WGK 1. Flash Point(F): Not applicable. Flash Point(C): Not applicable.