TMC647055 (Choline salt) is a potent nonnucleoside NS5B polymerase inhibitor of HCV replication . TMC647055 Choline salt has potent HCV combine activity with an IC 50 value of 82 nM. TMC647055 Choline salt can be used for the research of Hepatitis C virusAppearance:SolidIC50& Target:EC90: 0.3 μM (Huh7-Luc cell) . EC50: 82 nM (HCV)In Vitro:TMC647055 (Choline salt) has antiviral activity with an EC 90 value of 0.3 μM in Huh7-Luc cells. TMC647055 Choline salt has potent combine activity with an EC 50 value of 82 nM in cellular HCV assays. MCE has not independently confirmed the accuIn Vivo:TMC647055 Choline salt (compound 18a) (2mg/kg, iv.; 1mg/kg, po.) shows an acceptable PK profile, characterized by high oral bioavailability and high systemic exposure after single oral dosing of 10mg/kg, combined with a moderate plasma clearanceand lowBiological Activity:TMC647055 (Choline salt) is a potent nonnucleoside NS5B polymerase inhibitor of HCV replication . TMC647055 Choline salt has potent HCV combine activity with an IC 50 value of 82 nM. TMC647055 Choline salt can be used for the research of Hepatitis C virus. Specification: 0.99 Molecular Formula: C37H53N5O8S Molecular Weight: 727.91
- UPC:
- 12352107
- Condition:
- New
- Availability:
- 8-12 weeks
- Weight:
- 1.09 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- T658919-2mg
- Product Size:
- 2mg
