Armenian Hamster anti Mouse TNF Receptor I Antibody, Monoclonal (55R-170), could be used for Flow, WB, IP, Blocking, Functional Assays, Neutralization and so on.ApplicationFlow: ≤1.0µg/100w cellsWB: Use at an assay dependent concentration.IP: Use at an assay dependent concentration.Blocking: Use at an assay dependent concentration.Functional Assays: Use at an assay dependent concentration.Neutralization: Use at an assay dependent concentration.Protein FunctionReceptor for TNFSF2/TNF-alpha and homotrimeric TNFSF1/lymphotoxin-alpha. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Contributes to the induction of non-cytocidal TNF effects including anti-viral state and activation of the acid sphingomyelinase.
Specifictaions: Carrier Free, Low Endotoxin, Azide Free, Validated, ≥95%(SDS-PAGE&HPLC), See COA
Related Documents: https://ald-pub-files.oss-cn-shanghai.aliyuncs.com/aladdinsci/pdp/sds/1/AB131819-SCI_526563a80b828f30dced81d8724b1fe5.pdf
- UPC:
- 41106514
- Condition:
- New
- Availability:
- 5-10 days
- Weight:
- 1.09 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- Ab131819-10μg
- Product Size:
- 10μg