Biochem/physiol Actions TPA023 is a highly potent, functionally selective agonist for α:2-, α:3-, and α:5GABAA receptors that shows zero efficacy at a1GABAA subtypes. TPA023 exhibits anxiolytic and anticonvulsant effects in both
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TPA023 is a highly potent, functionally selective agonist for α2-, α3-, and α5GABAA receptors that shows zero efficacy at a1GABAA subtypes. TPA023 exhibits anxiolytic and anticonvulsant effects in both animals and humans but lacks sedative effects and abuse potential.
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