General description
Tributylphosphine (TBP) is a potential nucleophile. It acts as a weak base in organic solvents. It is an important catalyst for the acylation reactions. It is an efficient promoting reagent for the ring-opening reaction of various epoxides and aziridines. TBP in conjugation with 1,1′-(azodicarbonyl)dipiperidine (ADDP) constitutes Mitsunobu reagent. This reactive phosphine allows the formation of a strained lactone.
Application
Tributylphosphine was used in the preparation of silver nanoparticles (AgNPs) functionalized with an organometallic bifunctional thiol containing Pt(II) centers.
It may be used in the following processes:
- As reducing agent for alkyl disulfides and aromatic disulfides.
- As catalyst for the synthesis of 2-substituted 1,3-benzoselenazoles.
- As promoter for the ring opening of epoxides and aziridines with nucleophiles.
- As a reagent in the preparation of 6-substituted penicillanate esters by reduction of 6-bromo-6-substituted penicillanate esters in high diastereoselectivity.
- As a catalyst in the acylation reaction of alcohols.
- As a catalyst to prepare rotaxanes by the acylation of corresponding pseudorotaxanes using 3,5-dimethylbenzoic anhydride.
- As a catalyst to prepare vinyl thioethers by the Michael addition of ethanethiol to various alkynyl ketones.
- As a promoter in the conjugate addition of non-nucleophilic N-containing compounds with Michael acceptors.
- UPC:
- 51362403
- Condition:
- New
- Weight:
- 1.00 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- 90827-100ML