Tris(2-carboxyethyl)phosphine hydrochloride (C09-1050-223)

TCEP Hydrochloride is a water soluble, non-thiol, strong reducing agent shown to cleave disulfide bonds. Reports indicate that TCEP Hydrochloride can rapidly reduce stable alkyl disulfides, including DTT. Application：Tris(2-carboxyethyl)phosphine hydrochloride (TCEP. HCl) can be used:As a reducing agent for the reduction of sulfoxides, sulfonyl chlorides, N-oxides, and azides. It can also be used in azide-alkyne cycloaddition reaction in the presence of a copper catalyst.To reduce disulfide bonds in various proteins.As a reagent for the selective reduction of disulfides in water.To remove ruthenium-derived metathesis catalysts via aqueous washing of a crude reaction mixture when it is basified.As a reducing agent for the reduction of various alkyl disulfides such as trans-4,5-dihydroxy-1,2-dithiane.Water soluble reagent, used for selective reduction of disulfides. More stable than DTT and useful in mass spectrometry applications. Specification: 0.98 MDL Number: MFCD00145469 Molecular Formula: C9H15O6P·HCl Molecular Weight: 286.65 PubChem CID: 2734570 Isomeric SMILES: C(CP(CCC(=O)O)CCC(=O)O)C(=O)O.Cl Beilstein Registry Number: 3724376 Related Documents: https://ald-pub-files.oss-cn-shanghai.aliyuncs.com/aladdinsci/pdp/sds/1/T107252-SCI_4ba237cc4b4474be0dbd339b174f713e.pdf