It belongs to the trialkylphosphine class. Tris (2-carboxyethyl) phosphine (TCEP) is very effective in cleaving disulfide bonds in aqueous solution. It dissolves in water and is odorless, unlike other trialkylphosphines (tributylphosphine). It is also less toxic than 2-mercaptoethanol. These advantages make it better than the other reducing agents. Application：Tris (2-carboxyethyl) phosphine (TCEP) can be used in several downstream applications including SDS-PAGE, mass spectrometry, labeling with cysteine specific tags, and modification of cysteine containing compounds. It prevents oxidation of protein samples, which makes it a useful buffer component as it helps to preserve enzymatic activity. It has been used in the reduction and measurement of glutathione.Tris (2-carboxyethyl) phosphine (TCEP) has also been used:to cleave cysteine residues in a synthetic peptidein reduction buffer for RNA Sequential Probing of Targets (SPOTs) imagingfor the reduction of oligonucleotidesas reducing agent during mitochondrial isolation. Specification: 0.5 M, pH 7.0(aqueous solution; pH was adjusted with ammonium hydroxide) Molecular Formula: C9H15O6P·HCl Molecular Weight: 286.65 PubChem CID: 2734570 Isomeric SMILES: C(CP(CCC(=O)O)CCC(=O)O)C(=O)O.Cl Beilstein Registry Number: 3724376 Related Documents: https://ald-pub-files.oss-cn-shanghai.aliyuncs.com/aladdinsci/pdp/sds/1/T379846-SCI_e701d4ec529cfca2ede2d52a1e294f20.pdf
- UPC:
- 51111869
- Condition:
- New
- Availability:
- 8-12 weeks
- Weight:
- 10.02 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- T379846-100ml
- CAS:
- 51805-45-9
- Product Size:
- 100ml
- Hazard Statement Codes:
- H290
- Precautionary Statement Codes:
- P234
