Tris(dibenzylideneacetone)dipalladium(0)-chloroform adduct (C15-1246-076)

General description

Tris(dibenzylideneacetone)dipalladium(0)-chloroform adduct (Pd₂dba₃·CHCl₃) is reported to serve as effective precatalysts, or precursors to the active Pd(0) catalyst.

Application

Application Guide for Palladium Catalyzed Cross-Coupling Reactions

Tris(dibenzylideneacetone)dipalladium(0)-chloroform adduct (Pd₂dba₃·CHCl₃) was used in the following studies:

• To compose the catalytic system for the preparation of homoallylpalladium complexes.These complexes underwent in situ Stille type cross coupling with various vinyltin reagents to afford the cyclized products bearing allyl appendages.
• As palladium source in the asymmetric transformations of 3,4-epoxy-1-butene.
• As catalyst for the Heck cross-coupling reaction of iodobenzene with styrene.
• As cyclization catalyst.
• As catalyst for [2+2+2] cycloaddtion of didehydrotriphenylenes to the corresponding extended triphenylenes.
• As catalyst for the carbonylation of b,b-imidoyl iodides to the corresponding imidate esters used, in turn, to prepare cyclic, quaternary amino acids.