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trv056 (c09-1182-627)

TRV056 (C09-1182-627)

Aladdin

Catalog No.
C09-1182-627
Manufacturer No.
T648017-1mg
Manufacturer Name
Aladdin Scientific
Quantity
1
Unit of Measure
EA
Price: $91.47
List Price: $101.64

TRV056 is a Gq-biased ligand of the angiotensin II receptor type 1 (AT1R). TRV056 is efficacious in stimulating cellular Gq-mediated signaling. TRV056 can be used to develop the Gq-biased AT1R agonists.In VitroTRV056 is a “gain-of-function” ligand

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TRV056 is a Gq-biased ligand of the angiotensin II receptor type 1 (AT1R). TRV056 is efficacious in stimulating cellular Gq-mediated signaling. TRV056 can be used to develop the Gq-biased AT1R agonists.In VitroTRV056 is a “gain-of-function” ligand that have >10-fold greater allosteric coupling to Gq than AngII and is also more efficacious in stimulating cellular Gq-mediated signaling (e.g., IP1 generation). Compared to the endogenous ligand angiotensin II (AngII), “Gq-biased” AT1R agonists are more efficacious in stimulating Gq-mediated cellular signaling and in allosterically promoting Gq coupling. MCE has not independently confirmed the accuracy of these methods. They are for reference only.Form:Solid. Specification: 0.99 Molecular Formula: C52H74N14O13 Molecular Weight: 1103.23
UPC:
12352005
Condition:
New
Availability:
8-12 weeks
Weight:
1.06 Ounces
HazmatClass:
No
WeightUOM:
LB
MPN:
T648017-1mg
CAS:
812644-79-4
Product Size:
1mg


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