General description
Tyrosine Hydroxylase (TYH) is the rate-limiting enzyme of catecholamine biosynthesiss. TYH uses tetrahydrobiopterin and molecular oxygen to convert tyrosine to L-DOPA, a precursor to dopamine. Anti-TYH is sensitive and specific for peripheral neuroblastic tumors in the differential diagnosis from other tumors of childhood and shows high diagnostic utility. Anti-TYH has been shown to positively label all pheochromocytomas and sympathetic paragangliomas, and thus aids in differentiating them from their histologic mimics such as adrenocortical neoplasms.
Quality
United States - IVD
Canada - RUO
European Union - IVD
Japan - RUO
Physical form
Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide.
Preparation Note
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Other Notes
For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com
Legal Information
Cell Marque is a trademark of Sigma-Aldrich Co. LLC
- UPC:
- 51263011
- Condition:
- New
- Availability:
- 3-5 Days
- Weight:
- 1.00 Ounces
- HazmatClass:
- No
- MPN:
- 490M-18
