U-73343 (C007B-304436)

Product description：U-73343, works as a protonophore, is an inactive analog of U-73122 and can be used as a negative control. U-73343 dose-dependently inhibits acid secretion irrespective of the stimulant. U-73122 is a phospholipase C (PLC) and 5-LO (5-lipoxygenase) inhibitor with an IC50 of 1-2.1 µM for PLC。Application：U-73343 has been used for studying the role of phospholipase C (PLC) signaling in modulating epithelial Na+ channel (ENaC) function in gerbil Reissner′s membranes (RMs). U-73343 has also been used as a negative control for PLC inhibition in mechanically stimulated (MS) and its neighboring (NB) cells.U-73343 has been used in measuring the fluorescence of intracellular Ca2+. Specification: ≥98% Molecular Formula: C29H42N2O3 Molecular Weight: 466.7 PubChem CID: 114825 Isomeric SMILES: C[C@]12CC[C@H]3[C@H]([C@@H]1CC[C@@H]2NCCCCCCN4C(=O)CCC4=O)CCC5=C3C=CC(=C5)OC Related Documents: https://ald-pub-files.oss-cn-shanghai.aliyuncs.com/aladdinsci/pdp/sds/1/U276451-SCI_aa8b46e65e101338c053ecaac2a4c20e.pdf