A potent antagonist highly selective for GluK1 (Kb = 10 nM), GluK3 (IC50 = 23 nM), and GluK1/K5 (Kb = 8 nM) subtype kainate receptors. Does not interact with GluK2 and GluK2/K5 receptors. Low affinity to AMPA receptors (Kd = 83 µM). Does not interact with mGluR1 or NMDA receptors at concentration less than 10 µM. Often used in studying neuronal excitability and synaptic plasticity. Specification: 0.98 Molecular Formula: C₁₄H₁₅N₃O₆S Molecular Weight: 353.35 PubChem CID: 6420160 Isomeric SMILES: CC1=CN(C(=O)N(C1=O)CC2=C(SC=C2)C(=O)O)C[C@@H](C(=O)O)N Related Documents: https://ald-pub-files.oss-cn-shanghai.aliyuncs.com/aladdinsci/pdp/sds/1/U287652-SCI_d2c3dadb24e5a6a035da70265671e5e0.pdf
- UPC:
- 51361936
- Condition:
- New
- Availability:
- 8-12 weeks
- Weight:
- 0.96 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- U287652-10mg
- CAS:
- 902464-46-4
- Product Size:
- 10mg
- Precautionary Statement Codes:
- P264
