Product Describtion:UK 383367 is a novel procollagen C-protein (PCP) inhibitor being investigated for the treatment of post-surgical dermal scarring, which potently inhibits the activity of PCP with the value of 50% inhibition concentration IC50 of 44 nM, as well as a selective inhibitor of matrix metalloproteinases (MMPs) with values of IC50 >60,000 nM for MMP-2 and >10,000 nM for MMP-1, MMP-3, MMP-9 and MMP-4. Although the mechanism is not clear yet, UK 383367 also exhibits weak inhibitory effects against phosphodiesterase-4 (PDE-4) enzyme, including PDE-4a, PDE-4b, PDE-4c and PDE-4d, with values of IC50 of 1.8 μM, 1.5 μM, 2.4 μM and 0.9 μM respectively. Specification: 0.98 MDL Number: MFCD19690945 Molecular Formula: C15H24N4O4 Molecular Weight: 324.38 PubChem CID: 9818682 Isomeric SMILES: C1CCC(CC1)CCC[C@H](CC(=O)NO)C2=NC(=NO2)C(=O)N Related Documents: https://ald-pub-files.oss-cn-shanghai.aliyuncs.com/aladdinsci/pdp/sds/1/U125948-SCI_fc8f5214f7970b1bf347c2e8971a6ee9.pdf
- UPC:
- 51111855
- Condition:
- New
- Availability:
- 2 weeks
- Weight:
- 0.97 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- U125948-50mg
- CAS:
- 348622-88-8
- Product Size:
- 50mg
