application：UK-5099 has been used:as a mitochondrial pyruvate blocker to reduce pyruvate transportation into mitochondria in Roswell park memorial institute (RPMI) 1640 medium for prostatic cancer cell line culturein dimethyl sulfoxide (DMSO) stock, to study the effect of inhibiting pyruvate transport into mitochondria on pro-inflammatory responses in lipopolysaccharide activated macrophagesin topical treatment in order to study its effect on hair cycle induction in experimental mice.Product description：UK-5099 (PF-1005023) is a potent inhibitor of the mitochondrial pyruvate carrier (MPC). UK-5099 (PF-1005023) inhibits pyruvate-dependent O2 consumption with an IC50 of 50 nM. Specification: 0.98 MDL Number: MFCD19443867 Molecular Formula: C18H12N2O2 Molecular Weight: 288.3 PubChem CID: 6438504 Isomeric SMILES: C1=CC=C(C=C1)N2C=C(C3=CC=CC=C32)/C=C(/C#N)/C(=O)O Related Documents: https://ald-pub-files.oss-cn-shanghai.aliyuncs.com/aladdinsci/pdp/sds/1/U126881-SCI_4585dd8bd2686b86eab782f3dc7cc757.pdf
- UPC:
- 12352200
- Condition:
- New
- Availability:
- 1 day
- Weight:
- 0.97 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- U126881-50mg
- CAS:
- 56396-35-1
- Product Size:
- 50mg
