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URACIL B-D-ARABINOFURANOSIDE

Catalog No.
C005B-285013
Mfr. No.
U5377-250MG
Mfr. Name
Sigma-Aldrich
Qty/UOM
250
UOM
MG
Price: $1,012.27
List Price: $1,124.74

General description 1-β:-d-arabinofuranosyluracil (Ara-U) is the detoxification product or metabolite of 1-β:-d-arabinofuranosylcytosine (Ara-C). Uracil 1-β:-D-arabinofuranoside is the human metabolite of a cytostatic agent called

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General description

1-β-d-arabinofuranosyluracil (Ara-U) is the detoxification product or metabolite of 1-β-d-arabinofuranosylcytosine (Ara-C). Uracil 1-β-D-arabinofuranoside is the human metabolite of a cytostatic agent called cytarabine (CYT).

Application

Uracil 1-β-D-arabinofuranoside may be used as a reference compound in the analysis of cytostatics and metabolites in hospital wastewater by hydrophilic interaction chromatography/tandem mass spectrometry to demonstrate its analytical possibilities and limitations. It may also be used as a standard for chemical analysis to investigate the ecotoxicity and genotoxicity of cytotoxic antineoplastic drugs, like cytarabine (CYT) and their metabolites, like uracil-1-β-d-arabinofuranoside (AraU).

Biochem/physiol Actions

1-β-D-Arabinofuranosyluracil (ara-U) is capable of inhibiting proliferation of L5178Y mouse lymphoma cells at 17 μM concentration.

UPC:
51111662
Condition:
New
Availability:
3-5 Days
Weight:
1.00 Ounces
HazmatClass:
No
MPN:
U5377-250MG
CAS:
3083-77-0

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