Urokinase from human urine (C09-1079-480)

Physical form Lyophilized from 1 mL of 50 mM Tris-HCl, pH 7.4 with 100 mM NaCl, 0.1% PEG 6000, and 200 mM mannitol Physical properties High molecular weight form migrating at 54 kDa by SDS-PAGE under non-reducing conditionsUrokinase is a protease that cleaves plasminogen to form plasmin. It binds to cell surface receptors (uPAR) from which it regulates cell adhesion and migration during tissue remodeling and which also activate intracellular signaling pathways. Urokinase is composed of three domains: the amino terminal domain which is homologous to epidermal growth factor is attached through a central kringle domain to the protease domain in the carboxyl terminus. Specification: ≥85%,Potency ≥50000IU/mg，specific activeiy 120000IU/mg MDL Number: MFCD00132566 Molecular Formula: C21H25BrN2O3 EC Number: 232-917-9 PubChem CID: 33309 Isomeric SMILES: CC(C)OC(=O)NC1=CC2=C(C=C1)N=C(N2)C3=CSC=N3 Related Documents: https://ald-pub-files.oss-cn-shanghai.aliyuncs.com/aladdinsci/pdp/sds/1/U108373-SCI_d5e7fc1d15b5b0f3e326a73695b37ae5.pdf