General description
Native urokinase from human urine. A thrombolytic agent that converts plasminogen to plasmin. A mixture of high molecular weight (54 kDa) and low molecular weight (33 kDa) urokinase.
Note: 1 unit = 1 CTA unit = 0.7 Ploug units. 1 KU = 1000 units.
Warning
Toxicity: Standard Handling (A)
Unit Definition
One unit is defined as the amount of enzyme equal to an international standard tested by the fibrinolytic method of Johnson, et al.
Physical form
Lyophilized from 200 mM mannitol, 100 mM NaCl, 50 mM Tris-HCl, 0.1% PEG, pH 7.5.
Preparation Note
Prepared from urine of individuals that have been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
Reconstitution
Following reconstitution, aliquot and freeze (-70°C). Stock solutions are stable for up to 6 months at -70°C.
Reconstitute in distilled H₂O
Other Notes
Bell, W.R. 1975. Semin. Thromb. Res.2, 1.
Johnson, A.J., et al. 1969. Thromb. Diath. Haemorrh. 21, 259.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
- UPC:
- 51131704
- Condition:
- New
- Weight:
- 1.00 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- 672112-10KU