Valproic Acid β-D-Glucuronide

Valproic Acid β-D-Glucuronide is a metabolite of Valproic Acid. Valproic Acid is a branched chain, fatty acid which is reported to potentially enhance central GABAergic neurotransmission and inhibit Na|+|channels. Currently, the various molecular mechanisms of action of Valproic Acid have not been completely elucidated. Valproic Acid has been reported to be a potent inhibitor of histone deacetylases (HDACs)|in vitro|. Valproic Acid is also noted to relieve HDAC-dependent transcriptional repression and causes the hyperacetylation of histones in cultured cells. Additionally, Valproic Acid is reported to activate Wnt-dependent gene expression and to mimic trichostatin A in the inhibition of histone deacetylase.|Metabolites of Valproic Acid are also available as:|Valproic Acid |Valproic Acid, Sodium Salt |3-Hydroxy Valproic Acid |3-Keto Valproic Acid Sodium Salt |4-Hydroxy Valproic Acid Sodium Salt(Mixture of Diastereomers) |rac 5-Hydroxy Valproic Acid Sodium Salt |Valproic Acid β-D-Glucuronide Allyl Ester |Labelled forms of Valproic Acid are available as:|Valproic Acid-d6 |Valproic Acid-d6 β-D-Glucuronide |rac 5-Hydroxy Valproic Acid-d7 Sodium Salt. Specifications and Purity: ≥96%. Molecular Formula: C14H24O8. Molecular Weight: 320.34. PubChem CID: 88111. Isomeric SMILES: CCCC(CCC)C(=O)O[C@H]1[C@@H]([C@H]([C@@H]([C@H](O1)C(=O)O)O)O)O. Related Document: https://ald-pub-files.oss-cn-shanghai.aliyuncs.com/aladdinsci/pdp/sds/1/V352510-SCI_f17d9c0b07a8f9b22b699434fddd2e81.pdf.