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VANADYL RIBONUCLEOSIDE COMPLEXES BIOREAGENT BIOCHEMIKA FOR MOLECULAR BIOLOGY (C005B-238193)

Catalog No.
C005B-238193
Mfr. No.
94740-250MG
Mfr. Name
Sigma-Aldrich
Qty/UOM
250
UOM
MG
Price: $299.71
List Price: $333.01

Vanadyl ribonucleoside complexes are low molecular weight inhibitors of ribonucleases. Application Vanadyl ribonucleoside complexes (VDR) are transition state analogs that bind to active sites of many RNases, inhibiting their activity.

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General description

Vanadyl ribonucleoside complexes are low molecular weight inhibitors of ribonucleases.

Application

Vanadyl ribonucleoside complexes (VDR) are transition state analogs that bind to active sites of many RNases, inhibiting their activity. Because the RNases are not covalently modified by the complexes, VDR must be used at every stage of RNA extraction and purification. However, VDR also inhibit RNA polymerases and in vitro translation and therefore must be removed from final preparation of RNA.

Vanadyl ribonucleoside complexes has been used in hybridization mixture for RNA in situ hybridization.

Biochem/physiol Actions

The vanadyl ribonucleoside complex has the ability to block the formation of ribosomal subunit in Staphylococcus aureus. The complex exhibits anti-microbial activity These complexes also serve as powerful inhibitors of several enzymes with ribonucleolytic activity.

grade: for molecular biology. Quality Level: 100. product line: BioReagent. form: powder. suitability: in accordance for ribonuclease inhibition test. shipped in: wet ice. storage temp.: −. 20°C. Storage Class Code: 11 - Combustible Solids. WGK: WGK 3. Flash Point(F): Not applicable. Flash Point(C): Not applicable. Personal Protective Equipment: Eyeshields, Gloves, type N95 (US).

Shipping Information:

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UPC:
12352200
Condition:
New
Availability:
3-5 Days
Weight:
1.00 Ounces
HazmatClass:
No
MPN:
94740-250MG
Temperature Control Device:
Yes

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