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vincristine sulfate, apocynaceae sp. - cas 2068-78-2 - calbiochem

Vincristine Sulfate, Apocynaceae sp. - CAS 2068-78-2 - Calbiochem

Sigma-Aldrich

Catalog No.
C15-1222-608
Manufacturer No.
677181-10MG
Manufacturer Name
Sigma-Aldrich
Quantity
10
Unit of Measure
MG
Price: $816.00
List Price: $906.67

Indole alkaloid that binds to tubulin, inhibiting formation of microtubules. Depolymerizes microtubules.

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General description

Indole alkaloid that binds to tubulin, inhibiting formation of microtubules. Depolymerizes microtubules. Induces increase in micronuclei and delays cell cycle progression. Anti-neoplastic agent. Induces apoptosis in human lymphoma cells by disrupting microtubules.

Please note that the molecular weight for this compound is batch-specific due to variable water content.

Indole alkaloid that binds to tubulin, inhibiting the formulation of microtubules. Depolymerizes microtubules. Induces an increase in the micronucleus and delays cell cycle progression. Antineoplastic agent. Induces apoptosis in human lymphoma cells by distributing microtubules.

Biochem/physiol Actions

Cell permeable: no

Product does not compete with ATP.

Reversible: no

Warning

Toxicity: Carcinogenic / Teratogenic (D)

Other Notes

Chan, M.W., et al. 1998. Cancer Biochem. Biophys. 16, 347.
Hanauske, A.R., et al. 1994. Eur. J. Cancer30A, 1688.
Takano, Y., et al. 1993. Pathol. Res. Pract. 189, 187.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

UPC:
51411706
Condition:
New
Weight:
1.00 Ounces
HazmatClass:
No
WeightUOM:
LB
MPN:
677181-10MG


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