ß-Carotene is a red-orange terpene pigment originally found in various plants and fruits; it is a prodrug for vitamin A. ß-Carotene exhibits antioxidative, cytoprotective, anticancer, anti-inflammatory, anti-hyperlipidemic, and anti-obesity activities. ß-Carotene is used in research models to quantify antioxidative activity. In bone marrow cells, ß-carotene protects against radioactive isotope-induced DNA damage. In breast cancer cells, this compound induces cell cycle arrest and apoptosis, decreasing cellular viability. ß-Carotene decreases total cholesterol, VLDL and LDL levels, suppresses expression of SREBP2 and LDL-R, and increases expression of PPARa in vivo. In other animal models, this compound decreases body fat and adipocyte size and suppresses TNF-a-induced inflammation.
- UPC:
- 12352200
- Condition:
- New
- Availability:
- 3 Days
- Weight:
- 1.00 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- C0269-50 g
- CAS:
- 7235-40-7
